Biosurgery: Advancing Medicine through Biologically Derived Solutions

In recent years, the healthcare and medical devices market has undergone a remarkable transformation, largely fueled by advancements in technology and growth in innovation. One of the major standout developments in the healthcare industry is the rise of the biosurgery market and the related product demand, which has been making a significant impact on health outcomes. With cutting-edge innovations such as biodegradable scaffolds, stem cell therapies, and precision medicine, biosurgery has revolutionized surgical procedures, tissue repair, and wound management. The rise in technological innovation has increased demand for biosurgical products and techniques as they offer safer, more effective, and personalized solutions. 

As per DelveInsight’s assessment, the global biosurgery market is anticipated to grow at a CAGR of 9.23% during the forecast period of 2023-2028. The biosurgery market is experiencing a robust upward trajectory, driven by a convergence of influential factors. These include the escalating prevalence of cardiovascular diseases, a surging demand for plastic surgery procedures, and a rising incidence of cancers like prostate cancer. Additionally, the market is being invigorated by a notable surge in the introduction of innovative biosurgical products. As the healthcare industry continues to embrace the potential of biosurgery, it is poised to witness sustained growth and innovation, ultimately benefiting both medical professionals and patients seeking advanced and tailored healthcare interventions. With each passing day, biosurgery continues to shape the future of the healthcare market outlook, leading to better treatment outcomes and patient satisfaction.

What is Biosurgery? 

Biosurgery is a medical field that utilizes biologically derived materials to aid in surgeries and wound care. In the world of modern medicine, the field of biosurgery has emerged as a pivotal player, offering innovative applications and solutions. It encompasses techniques like hemostasis, tissue repair, and wound management using natural or engineered biological substances. Biosurgery aims to improve surgical outcomes, promote tissue regeneration, and enhance patient recovery. Biosurgery, characterized by the utilization of biological or biologically derived materials, holds immense promise in revolutionizing the way we approach surgery and post-operative care. Over the past few years, several groundbreaking advancements have been observed in the biosurgery market. 

Biosurgery Product Type and Their Key Applications

Biosurgery encompasses a diverse range of product types designed to enhance surgical procedures, wound management, and tissue repair. These product categories include hemostats, sealants, adhesion barriers, and soft tissue grafts, among others. Each product serves unique roles in improving patient outcomes and advancing the field of surgery. Some of the fundamental aspects of these products are as follows:

• Hemostasis: Hemostasis helps in the prevention of bleeding during operations and is one of the major product types of biosurgery. Safer surgeries are made possible by the use of biosurgical agents like collagen, gelatin, or thrombin, which encourage blood clotting and minimize bleeding.
• Bone Grafts: Orthopedic surgery benefited immensely from biosurgery product bone grafts, that help in replacements and encourage bone healing and regeneration. These substances make it easier to fix fractures and fuse bones.
• Tissue Repair and Regeneration: In order to repair and regenerate tissue, biosurgery is essential. It aids in the repair or replacement of injured tissues, it entails the use of biological grafts, implants, or scaffolds created from tissues or biomaterials. This factor is very important in regenerative medicine and reconstructive surgery.
• Sealant: Sealants are medical substances or products designed to seal or close wounds, incisions, or tissue surfaces during surgical procedures. There are various types of sealants such as biological sealants, synthetic sealants, and combination sealants. They are used in a variety of surgical specialties, including cardiovascular surgery, general surgery, neurosurgery, and orthopedic surgery, among others. The choice of sealant depends on the specific surgical procedure, the type of tissue involved, and the desired outcome.
• Adhesion Barriers: Adhesion barriers in biosurgery are medical devices or substances used to prevent abnormal tissue adhesions or scar formation after surgery. Their importance lies in reducing the risk of postoperative complications, such as tissue attachments or adhesions, which can lead to pain, organ dysfunction, and the need for additional surgical interventions.
• Wound Care Products: Biosurgical products are essential in wound care, where biological dressings made from human or animal tissues protect and aid the healing of wounds. These products can provide a natural environment for tissue regeneration and minimize infection risks.
• Soft Tissue Augmentation: In cosmetic and reconstructive surgery, biosurgery techniques are employed to enhance or reshape soft tissues. Substances like hyaluronic acid or autologous fat are injected to achieve desired cosmetic results.
• Infection Control: Some biosurgical materials possess antimicrobial properties, helping to reduce the risk of infections during and after surgery. This is particularly crucial in preventing post-operative complications.

Biosurgery Product Market Segment Analysis

According to the assessment by DelveInsight, in the biosurgery product types segment, the hemostats are anticipated to secure a substantial share of revenue in the years ahead. This is attributed to several noteworthy factors that fuel the growth of the hemostats products demand. Hemostats, renowned for their efficacy in clamping small blood vessels to control hemorrhaging and securing superficial fascia during the process of undermining and debriding wounds, are considered indispensable instruments in surgical procedures. Furthermore, their role in facilitating exposure, exploration, and visualization of deeper wound areas, along with their ability to promote the formation of stable clots that are less susceptible to rupture, adds to their appeal.

However, it’s imperative to note that the growing demand for hemostats is not the sole driver of biosurgery market growth. While these attributes certainly contribute significantly, the market’s expansion is further propelled by technological advancements and the successful commercialization of biosurgery products. These developments play a pivotal role in ensuring that the biosurgery market remains dynamic and competitive, offering innovative solutions to meet the evolving needs of healthcare professionals and patients alike. Nonetheless, to sustain this growth, it is crucial for the industry to continue pushing the boundaries of technology and product innovation while addressing potential challenges and market dynamics.

Biosurgery Market Dynamics and Outlook

A significant catalyst propelling the heightened demand for biosurgery products stems from the escalating prevalence of cardiovascular diseases. Biosurgery products play a pivotal role in cardiovascular surgeries due to their safety, efficacy in preventing bleeding, and their ability to facilitate post-surgical wound healing. Consequently, the expanding occurrence of cardiovascular ailments is expected to catalyze a surge in demand for biosurgery, thereby propelling the overall biosurgery market’s growth trajectory in the upcoming years. This trend underscores the critical role that biosurgery plays in addressing the healthcare needs of a population increasingly affected by cardiovascular conditions.

Furthermore, another pivotal factor fueling the expansion of the biosurgery market is the surging demand for plastic surgery. In 2020, the United States witnessed a substantial uptick in cosmetic procedures, with 2.3 million being cosmetic surgical operations and 13.2 million being minimally invasive procedures, totaling 15.6 million cosmetic interventions. Additionally, reconstructive procedures experienced a 3% growth compared to 2019, reaching 6.8 million procedures. This remarkable surge in the plastic surgery industry led to the increasing inclination toward cosmetic and reconstructive enhancements, which, in turn, is expected to significantly boost the demand for biosurgery products. This growing synergy between plastic surgery and biosurgery creates a conducive growth environment for the overall biosurgery market, reflecting the industry’s adaptability to evolving consumer preferences and aesthetic aspirations.

Nonetheless, the global biosurgery market’s growth trajectory may face impediments due to the escalating costs associated with surgical procedures and the concomitant complications, including infections and post-operative pain. These cost factors pose challenges for both patients and healthcare systems, potentially discouraging some from opting for surgical interventions. Additionally, the risk of complications can lead to hesitancy among patients. Therefore, while the biosurgery market holds promise, it must contend with these critical issues and explore ways to mitigate them to ensure sustained growth and accessibility in healthcare.

Biosurgery Companies and Innovation 

Globally, several major MedTech companies are active in the biosurgery market. Some of the major biosurgery companies actively operating in the market include BD, Baxter, SAMYANG HOLDING CORPORATION, B. Braun Melsungen AG, Stryker, Integra LifeSciences, Hemostasis LLC, Biom’Up, Pfizer, Ethicon US LLC (Johnson & Johnson Services Inc), CryoLife Inc, Zimmer Biomet, Kuros Biosciences, Orthofix US LLC, Tissue Regenix, Betatech Medical, Meril Life Sciences Pvt. Ltd, RTI Surgical, AROA BIOSURGERY LIMITED, BioCer Entwicklungs-GmbH, among others. These companies are playing a pivotal role in driving innovation within the biosurgery segment, shaping the market’s outlook significantly. Through extensive research and development efforts, these companies are continuously introducing groundbreaking biosurgical products and technologies to the market. 

Similarly, companies are actively investing in cutting-edge solutions such as biodegradable scaffolds, stem cell therapies, and advanced hemostatic agents, which not only enhance surgical procedures but also improve health outcomes. Additionally, several new startups are entering the segment to cater to the growing demand for personalized medicine by offering tailored biosurgical solutions. By actively pushing the boundaries of biosurgery and responding to evolving healthcare needs, these companies are set to play an instrumental role in shaping a promising and dynamic future for the biosurgery market in the upcoming years. 

Recent Developmental Activities in the Biosurgery Product Development Domain

The field of biosurgery is dynamic and continuously evolving, driven by advancements in biotechnology, regenerative medicine, and the quest for safer and more effective surgical solutions. Some of the major notable clinical, commercial, and regulatory advancements in the biosurgery market include:

• In February 2022, Gunze Limited, announced that it has received medical device approval to manufacture and sell TENALEAF™, the first sheet-type absorbable adhesion barrier made in Japan. During open surgery and minimally invasive surgery, this device gives surgeons a new choice that can facilitate simple manipulation, provide a modest amount of adhesive strength for repositioning, and allow for conformable insertion.
• In February 2022, Baxter announced the acquisition of Seprafilm Adhesion Barrier which is used as an adjunct to limit the incidence, extent & severity of adhesions in certain pelvic and abdominal surgeries.
• In December 2021, BD announced the acquisition of Tissuemed, Ltd., a privately held company and an industry leader in developing self-adhesive surgical sealant films. Tissuemed’s lead product, Tissuepatch™, is a proprietary sealant technology that bonds to tissue to help control internal bleeding or stop leakage from surgical wounds.
• In July 2021, Medcura in partnership with ASO announced the launch of a high-performance, antibacterial hemostatic gel, Rapid-Seal®. It can be easily applied for irregular injuries where bandages could be inconvenient, as well as powders are messy & can cause discomfort.
• In April 2021, Aroa Biosurgery launched a new product named Myriad Morcells™, a morcellized (powder) format of Myriad Matrix™ which easily conforms to maximize interaction with uneven wound beds.

Biosurgery Market: Key Conclusion and Analysis

Biosurgery is at the forefront of medical innovation, leveraging biological materials and cutting-edge technologies to enhance surgical procedures, tissue repair, and wound management. With its diverse applications, from hemostasis to tissue regeneration and infection control, biosurgery offers a range of benefits for both patients and surgeons. The future outlook of the biosurgery market appears exceptionally promising, with several key factors poised to shape its trajectory. Technological innovation is set to be a driving force, as emerging technologies like 3D printing, advanced biomaterials, and regenerative medicine techniques are anticipated to immensely revolutionize the healthcare field. These innovations are enabling the creation of highly customized and effective biosurgical solutions. Simultaneously, robust product development activities, fueled by a commitment to addressing unmet medical needs, are likely to yield a steady stream of cutting-edge biosurgery products.

Furthermore, regulatory approval processes are becoming more streamlined, facilitating the market entry of innovative and advanced biosurgical technologies and products. Regulatory agencies recognize the potential of biosurgery in improving patient outcomes and are working collaboratively with manufacturers to ensure safety and efficacy standards are met. Similarly, MedTech companies are playing a pivotal role by investing in research and development activities, pushing the boundaries of what’s possible in biosurgery, and bringing numerous innovations to market. The commitment by the companies to innovation not only fuels market growth but also drives competition, leading to improved product quality and affordability.

Additionally, the surge in demand for biosurgery solutions, driven by an aging population, a rise in chronic diseases, and an increased focus on minimally invasive procedures, further led to a positive outlook for the biosurgery industry. As demand continues to grow and more products gain regulatory approval, the biosurgery market is set to witness sustained expansion, benefiting both healthcare providers and patients through enhanced surgical outcomes and improved post-operative care.