Dermatology

Generalized pustular psoriasis (GPP) is a severe form of rare skin condition caused by abnormal inflammation.  It is a type of psoriasis, which is characterized by long-lasting abnormal dry-skin patches all over the body. Bodies of the patients suffering from GPP develop red and tender skin covered with pus-filled blisters. The skin inflammation is also accompanied by fever, headache, fatigue, nausea and abnormally high number of white blood cells contained in the pustules. Researchers revealed that the mutations in the gene like IL36RN and CARD14, increase the risk of generalized pustular psoriasis. These genes are responsible for transcribing into some crucial ...