Follicle Stimulating Hormone (FSH) is a glycoprotein secreted by the anterior pituitary, necessary for mammalian reproduction. FSH helps in development and maturation of gonads at puberty, and the hormone acts by binding to FSH receptor. Endometriosis is an extra growth of endometrial tissues in the abdominal cavity. As Follicle-stimulating hormone receptor (FSHR) is present on endothelial cells of blood vessels and endometrial glands of the proliferative and secretory endometrium, FSH therapy can be very helpful in curing endometriosis.
Some of the therapies for endometriosis treatment include non-steroidal anti-inflammatory drugs (NSAIDs), progestins (medroxyprogesterone), a combination of estrogens and progestins, synthetic androgens (danazol), and gonadotropin-releasing hormone analogues with or without hormone replacement therapy and many more. Other therapies include transcutaneous electrical nerve stimulation (TENS) may be effective for the treatment of women with deep endometriosis.
For treating endometriosis, various hormonal therapies are in the market, by different companies like Teva Pharmaceuticals, Healthcare Pharmaceuticals, and Bayer. Teva has launched a drug named as Sprintec; Dienogest is marketed by Bayer HealthCare Pharmaceuticals and is considered as long term treatment for Endometriosis when administered properly.
