Primary biliary cholangitis (PBC), earlier known as primary biliary cirrhosis, is an autoimmune disorder that leads to the gradual destruction of intrahepatic bile ducts resulting in periportal inflammation cholestasis. Prolonged hepatic cholestasis subsequently leads to cirrhosis and portal hypertension.
As per longitudinal studies of trends in primary biliary cholangitis among patients under routine clinical care in the United States, it has been found that from 2006 to 2014, the prevalence of PBC increased from 21.7 to 39.2 per 100,000 persons.
As per the latest “Primary Biliary Cholangitis Epidemiology Report” published by DelveInsight, it was found that pr...