Angelman syndrome (AS) is a complex genetic rare disorder that affects the nervous system. The first sign of a child suffering from Angelman syndrome is a delay in development, such as the inability to sit without support or making incoherent babbling sounds. The hallmarks of the syndrome constitute severe physical disabilities, delayed development, intellectual disability, severe speech impairment, and problems with movement and balance (ataxia). Often affected children experience recurrent seizures (epilepsy) and have a small head size (microcephaly).
Angelman syndrome is a result of the missing or dysfunctional gene known as UBE3A. The gene is responsible for t...
