Genetic Disorders

Mucopolysaccharidosis I (MPS I) (Hurler Syndrome) – a lesser developed window Mucopolysaccharidosis (MPS) is a group of rare, hereditary and incurable “storage diseases”, which is named after mucopolysaccharides (sugars bound to proteins). The stored mucopolysaccharides are called as glycosaminoglycans (GAGs).  GAGs are building blocks for bones, cartilage, tendons and many other tissues of the body. Normally the GAGs are catabolized with use of enzymes found in the lysosomes and eliminated from the body. Whereas in MPS the cycle breakdowns and each MPS disorder is caused by a deficiency in the activity of a single, specific lysosomal enzyme required for GAG degr...