Genetic Disorders

Hereditary Angioedema (HAE) is an autosomal dominant disease which is caused by a deficiency in functional C1 inhibitor. It is a rare hereditary disease which is characterized by painful, unpredictable, recurrent attacks of inflammation and swelling affecting the hands, feet, face, abdomen, urogenital tract, and the larynx. This genetic disease is caused by the production of either inadequate or nonfunctioning C1-Inhibitor protein. The C1-Inhibitor helps in the regulation of the complex biochemical interactions of blood-based systems which are involved in disease fighting, inflammatory responses and coagulation. It is very rare and potentially life-threatening genetic...