Hematological Disorders

Beta Thalassemia (β-Thalassemia) is a blood disorder characterized by reduced synthesis of the hemoglobin subunit beta (hemoglobin beta chain) that results in microcytic hypochromic anemia, an abnormal peripheral blood smear with nucleated red blood cells, and reduced amounts of hemoglobin A (HbA) on hemoglobin analysis. General occurrence of severe and untreated Beta Thalassemia symptoms include severe anemia, with an Hb level of 3−6 g/dL, massive hepatosplenomegaly, severe growth retardation, and bony deformities. Beta Thalassemia treatment therapy involves regular blood transfusions, iron chelation, bone marrow transplant and novel gene therapy options. Surgery for...