Vir's Hepatitis B drug shows positive results in phase 2
The hepatitis B drug of Vir Biotechnology has shown promising results. Its gene-silencing drug trim levels of the hepatitis B surface antigen in a small phase 2 study in patients who are already taking antiretroviral drugs.
The drug, VIR-2218, is made to prevent the expression of all hepatitis B proteins, including its surface antigen, HBsAg. The prospect was called ALN-HBV-02 before Alnylam licensed it to Vir in 2017 as a part of an infectious disease agreement which is worth up to USD 1 billion.
The study tried four dose levels of VIR-2218 in 24 patients who were getting nucleos(t)ide revers...
