Adult-onset Still’s Disease (AoSD), alternatively known as systemic-onset juvenile idiopathic arthritis, is a rare systemic inflammatory disorder of unknown etiology. There are three main patterns of AoSD’s clinical course: monophasic, intermittent, and chronic. Although there is an approximately equal distribution in each category, some studies have shown the chronic articular pattern to be more common.
According to the Arthritis Foundation (n.d.), AoSD is a type of arthritis with symptoms like fever, rash, and joint pain and was thought to be autoimmune or autoinflammatory. According to Orphanet (n.d.), the estimated AoSD prevalence is 1–9/100,000 popu...
