Actinium Announces Positive Top-line Results from Pivotal Phase III SIERRA Trial of Iomab-B
Actinium Pharma is on track to submit its targeted radiotherapy for AML patients requiring a bone marrow transplant in the United States, boosted by top-line data from a pivotal trial. The SIERRA trial of Iomab-B, an antibody armed with a radioisotope designed to deliver targeted treatment to tumors while sparing healthy tissues, was completed on 31 October 2022, according to the company. SIERRA enrolled 150 patients with relapsed or refractory AML who were randomly assigned to either Iomab-B or standard therapy as a conditioning regimen before transplant.
According to Ac...