Bristol-Myers Squibb’s Opdivo Gets FDA Approval for Esophageal Cancer
The FDA has approved two combination drug regimens based on Bristol-Myers Squibb’s PD-1 inhibitor Opdivo for previously untreated advanced Esophageal Cancer, encroaching on the territory belonging to Merck & Co’s rival Keytruda. The latest approvals are for Opdivo (nivolumab) in combination with chemotherapy or BMS’ CTLA4 inhibitor Yervoy (ipilimumab) as first-line therapy for Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) that cannot be treated surgically. Both regimens improved overall survival compared to chemotherapy alone in the Phase 3 study, which was reported to be t...