Gene-edited T cells for diabetes treatment
The Scientists at the Seattle Children's Research Institute and the Benaroya Research Institute have got a promising finding that will turn off the destructive autoimmune response in Type 1 diabetes. This comprises editing the genes of patients' T cells.
The team presented that by gene-editing CD4+ T cells to express a protein called FOXP3, they could transform the cells into cells having the immunosuppressive properties, as published in the journal Science Translational Medicine. The researchers further engineered the cells to be antigen-specific from T cell receptor (TCR) technology, which has been discovered as an an...