Avrobio taps ADC of Magenta for enhancing gene therapy conditioning
Avrobio is working to make conditioning safer. The company is collaborating with Magenta Therapeutics to check antibody-drug conjugate.
Under the agreement, the partners will evaluate Magenta’s lead conditioning program, MGTA-117, with at least one of the gene therapies of Avrobio. Each company will have the rights for their respective programs, but Avrobio will pick up for clinical trials, including MGTA-117.
The lead program of Avrobio is a gene therapy for Fabry disease named AVR-RD-01. It is based on CD34+ stem cells, which have been modified utilizing a lentiviral vector to express the g...