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What is Triple Negative Breast Cancer? Triple Negative Breast Cancer (TNBC) is defined as a heterogeneous breast cancer phenotype where the estrogen and progesterone receptor are negative, and there is a lack of overexpression of HER2, as assessed by immunohistochemistry (IHC), or the absence of its gene amplification, as assessed by fluorescence in situ hybridization technique. There has been plethora of cases that showed China accounted for 43% of the total diagnosed incident cases, followed by the US for 24% of these cases, out of all TNBC cases in G8 countries in 2016. Amongst the EU-5 countries, Germany had the highest diagnosed incidence (32%) of TNBC in the year...
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