T-cell receptor (TCR)-dependent treatment involves modified immune cells aimed at attacking particular tumor indicators. This treatment approach necessitates a systematic procedure including patient evaluation (e.g., for HLA-A*02:01 and precise tumor markers), collecting immune cells, creating the altered TCR product, reducing immune activity, and administering the TCR-based treatment.
The Role of TCRs in Recognizing and Targeting Abnormal Cells
TCRs play a pivotal role in the immune system’s ability to recognize and target abnormal cells within the body. These specialized proteins are expressed on the surface of T cells, a type of white blood cell that orchestr...