Immune checkpoint inhibitors are drugs that inhibit immune checkpoints. These drugs allow immune cells to respond more strongly to cancer by blocking them. This blocks the “off” signal, allowing T-cells to kill cancer cells.
Checkpoint inhibitors can be used to treat a variety of cancers, including lung cancer (NSCLC and SCLC), melanoma, breast cancer (triple-negative, metastatic breast cancer), Hodgkin lymphoma, Urothelial carcinoma, Renal cell cancer (RCC), and others. Immune checkpoint inhibitors outperform other commonly used treatment therapies, such as chemotherapy, in terms of survival time and potency against cancer cells.
Nonetheless, a few side effects...
