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Oncology

Pharma News for Amgen, AstraZeneca, Sanofi, Anavex, Sensorion, GSK

Notizia - Recent Pharma, Healthcare and Biotech Happenings

Amgen’s Olpasiran Candidate; GSK’s Novel Antibiotic for Urinary Tract Infections; AstraZeneca and Sanofi’s Beyfortus Approval; FDA Orphan Designation to Anavex’s Anavex2-73; FDA Rare Pediatric Disease Designation to Sensorion’s OTOF-GT; GSK’s Blenrep Fails in Phase III Trial in R/R Multiple Myeloma

Amgen Reports Promising Mid-stage Results for its Olpasiran Candidate Amgen has reported encouraging mid-stage results for its olpasiran candidate for lowering lipoprotein(a) - a risk factor for atherosclerotic cardiovascular disease - and now plans to move forward with a phase III program as soon as possible. The OCEAN(a)-DOSE trial’s final results, published in the New England Journal of Medicine, showed that the siRNA drug reduced Lp(a) levels compared to placebo at all four doses tested, with doses above 75 mg given every 12 weeks cutting levels by 95% or more after six months. Amgen still needs to demonstrate that the reduction in Lp(a) is associated ...

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