FDA Grants Fast Track Designation to VB-111 for Platinium-resistant Ovarian Cancer
The FDA has given VBL Therapeutics’ VB-111 (ofranergene obadenovec), a targeted anticancer viral gene therapy, fast track designation for use as a viable therapeutic option in patients with platinum-resistant Ovarian Cancer.
VB-111 is intended to target a wide spectrum of solid tumors, including ovarian cancer, using a dual mechanism. The strategy combines tumor vascular blockage with an anticancer immune response. Prior findings from a phase 1/2 trial showed that VB-111 coupled with paclitaxel was efficacious and safe in this patient population.
Approximately half of the 21 pa...