Novo Nordisk Reports Phase III Results of Concizumab Drug for Hemophilia A or B
Novo Nordisk has announced Phase III results for their concizumab drug for hemophilia A or B, demonstrating efficacy in preventing bleeding events and paving the way for regulatory filings later this year. Concizumab, an anti-tissue factor pathway inhibitor (TFPI) antibody, reduced the number of treated bleeds in patients by 86% when given as a once-daily subcutaneous injection in the Explorer7 trial. The findings were presented at the International Society on Thrombosis and Haemostasis (ISTH) annual meeting.
It also achieved a median annualized bleed rate (ABR) of 0.0, compared to 9...