Patients suffering from Colorectal Cancer (CRC) usually gets affected with distant organ metastases spreading the tumor to other parts of the body. Patients with unresectable or borderline resectable Colorectal liver metastases (CRLM) are given Neoadjuvant Chemotherapy (NC) to limit liver resection and to lower down the tumor burden. But the possible chances of chemotherapy-induced liver damage and associated effects do not get ruled out. Chemotherapy can potentially damage the healthy tissue surrounding the tumor.
So, the discovery of a tissue-based molecular biomarker which will only target primary tumor proved to be a ray of sunshine in the rain.
A recent s...
