Oncology

Immune checkpoints are the regulators of immune activation. They play a key role in maintaining immune homeostasis and preventing autoimmunity. Immune checkpoint activators are small molecules responsible for maintenance, modulation, and regulation of immune responses. Its significance in immune-therapeutics is backed by its functionality to activate the immune checkpoint proteins that are down-regulated by tumors, leading to the activation of the immune system as a response to combat the tumor. The recent trend with Immune checkpoint activators is their combined use with chemotherapy. These acts on certain immune cells that need to be activated at certain or specific ...