Oncology

Mammalian Target of Rapamycin (mTOR) is always in limelight for its wider application. It is a protein of a 289-kDa long chain contains serine and threonine kinase, and was first identified when rapamycin (Sirolimus) was discovered. mTOR helps in the synthesis of important cellular proteins which has a major impact in various aspects of cell growth and differentiation, progression of cell cycle, protein degradation, angiogenesis and apoptosis. It regulates various growth factors and mostly in cancer mTOR pathway is more active. It is used in most of the therapy areas such as Onclogy, Renal dysfunction, cardiovascular disease. The researcher also identified its applicat...