There has been a renaissance in gene therapy attempts, spurred partly by the discovery and understanding of novel gene delivery vectors. Adeno-associated virus (AAV) is a non-enveloped virus that may be designed to carry DNA to target cells and has sparked considerable interest in the area, particularly in clinical-stage experimental therapy techniques. The capacity to create recombinant AAV particles devoid of viral genes but carrying DNA sequences of interest for diverse therapeutic purposes has thus far proven to be one of the safest gene therapy techniques.
Adeno-associated virus (AAV), discovered 5 decades back in mid-1960s from laboratory adenovirus (Ad...