Neovascular age-related macular degeneration (nAMD or Wet AMD) is a progressive retinal condition and a primary cause of central vision loss among individuals over 60 years old. While it represents only 10–15% of overall AMD cases, it is responsible for nearly 90% of severe vision impairment linked to the disease. The condition is driven by abnormal blood vessel growth beneath the retina, leading to leakage, scarring, and irreversible central vision damage. Anti-vascular endothelial growth factor (VEGF) therapies have transformed outcomes for patients; however, treatment burden, limited durability, and ongoing challenges continue to affect long-term disease management...
