Trophoblast cell surface antigen-2 (TROP-2) is a 35-kDa protein found on cell membranes, made of sugars and a protein chain, serving as a transmitter of calcium signals. It is produced by the TACSTD2 gene and shares a structural similarity with the epithelial cell adhesion molecule (EpCAM).
TROP2, although identified for its promising potential in cancer treatment some years ago, is now emerging as a significant protein target. With the rise of targeted therapies and immunotherapies, TROP2 has gained attention due to its crucial role in cancer cell proliferation and spread. Its increased presence in various cancers further solidifies its status as a valuable protei...