In recent years, the misuse and abuse of opioids have become a growing concern worldwide, with devastating consequences for public health. While the immediate dangers of opioid overdose are well-documented, a silent and potentially lethal complication often lurks in the shadows—opioid-induced respiratory depression.
Opioid-induced respiratory depression (OIRD) is a serious condition resulting from decreased respiratory drive, sedation, and upper airway obstruction caused by opioids. If not identified and treated promptly, OIRD can be fatal. Comorbidities like sleep apnea, renal and hepatic diseases, COPD, cardiac issues, and obesity elevate the risk of OIRD. ...