Lupus nephritis is a serious and common complication of systemic lupus erythematosus (SLE), characterized by inflammation of the kidneys that can lead to progressive organ damage and increased mortality. Approximately one-third of adults with SLE present with lupus nephritis at diagnosis, and up to half will develop it over time. Often asymptomatic in its early stages, lupus nephritis may eventually manifest with edema, changes in urine output, and elevated blood pressure—signs of impaired renal function. Early detection and timely intervention are critical to preserving kidney health and improving long-term outcomes.
Lupus nephritis affects 1.7 million people glob...
