Epstein–Barr virus (EBV), also known as human herpesvirus 4 (HHV-4), was discovered in the 1960s as an inescapable virus that infects almost 95% of the world’s population and causes nearly 1% of all cancers. Besides, the virus is a leading cause of infectious mononucleosis (IM) and is associated with different subtypes of lymphoma, sarcoma, and carcinomas, such as Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, nasopharyngeal carcinoma, and gastric carcinoma. However, despite years of research and studies, the actual reason behind EBV-linked cancers remains unclear. In most people, the primary infection occurs in childhood and remains asymptomatic. However, nearly 50% of ...
