IgG4-related disease (IgG4-RD) was first identified as a systemic condition between 2001 and 2003 in a group of Japanese patients. Subsequently, in 2011, Japan’s Ministry of Health, Labor and Welfare introduced the first diagnostic criteria for the disease.
Although specific data on the period prevalence of IgG4-RD in the United States is limited, findings from long-term research at Massachusetts General Hospital led DelveInsight to estimate that approximately 57,000 individuals in the US were diagnosed with IgG4-RD in 2024. This number is projected to rise throughout the forecast period (2025–2034), driven by increased disease awareness from new therapies, a growi...
