AstraZeneca’s COVID-19 vaccine data suggest single-dose efficacy
The full data from late-phase trials of AstraZeneca’s COVID-19 vaccine have pointed to the potential for AZD1222 to work after a single dose and limit asymptomatic cases; however, missed main questions regarding the efficacy of the candidate.
The results that were posted in The Lancet restate the headline findings shared by AstraZeneca and its partners at the University of Oxford. In a pooled analysis of 11,636 participants enrolled in two separate clinical trials in the U.K. and Brazil, the efficacy of two doses of the vaccine was 70%. The paper includes the detail that protection against the symp...