Rare Diseases

It is a well-known fact that where there is stem cell transplantation, there is Graft vs Host Disease (GVHD). The concept arose 2 decades ago and is not rare- it is a common complication of allogeneic hematopoietic stem cell transplantation (HSCT) that occurs when the donated (graft) cells are rejected, and attack the host's cells as foreign. Chronic GVHD is a major area of concern as it can last for years or a lifetime, leading to debilitated and life-threatening condition. Approximately 40 percent of patients develop chronic GVHD after 100 days of transplant. The number of cases of GVHD depends on the number of allogeneic cell transplants (HCTs) and the transplanta...