Astellas & AviadoBio Sign Exclusive Deal for Gene Therapy AVB-101 in Frontotemporal Dementia
AviadoBio Ltd. and Astellas Pharma Inc. have announced a strategic partnership under an exclusive option and license agreement for AVB-101, an investigational AAV-based gene therapy currently in Phase I/II development for patients with frontotemporal dementia caused by progranulin mutations (FTD-GRN). Frontotemporal dementia is a rare, aggressive form of early-onset dementia that typically leads to death within three to 13 years after diagnosis. It often results in a rapid decline in cognitive and executive functions, behavioral changes, language loss, apathy, and mobil...