Algernon receives positive FDA feedback on Phase IIb chronic cough trial
The US Food and Drug Administration (FDA) has given positive feedback for Algernon Pharmaceuticals’ Phase IIb clinical trial of NP-120 (ifenprodil) for chronic cough treatment.
A receptor antagonist of N-methyl-D-aspartate (NMDA), ifenprodil precisely acts on the NMDA-type subunit 2B (GluN2B). The agency offered the feedback at the pre-Investigational New Drug (pre-IND) meeting for the therapy.
As per an announcement, the meeting proffered guidance on the Phase IIb protocol design submitted by Algernon and the endpoints, which were chosen. Moreover, the FDA sought completion of standard...