DelveInsight

Nov 03, 2017

AstraZeneca and Incyte are about to enter into Clinical Trial Collaboration in Early Lung Cancer The exclusive collaboration for the study population allows the two companies to conduct a Phase 3 trial. Aim of this study is to evaluate patients with locally-advanced (Stage III), unresectable non-small cell lung c...

Oct 16, 2017

Wet AMD is a chronic eye disease that causes blurred vision or a blind spot in a person’s visual field. It is characterized by abnormal blood vessels that leak blood and fluids into the macula, a region of the eye that is responsible for sharp, central vision. Age-related macular degeneration (AMD) is a common eye c...

Oct 10, 2017

Novo petitions FDA to require copies of Victoza to conduct clinical trials With one drugmaker already trying to pry patent protection off of Novo Nordisk’s blockbuster Victoza before its 2022 expiration, the insulin specialist has taken new steps to deter copies. The Danish drugmaker has filed a citizen petition arg...

Oct 09, 2017

Natural killer cells are a type of lymphocytes and are key components of the innate immune system. They are highly specific predators that play a major role in the host rejection of both tumors and virally infected cells. NK cells are derived from the common lymphoid progenitor cells (lymphoblasts), which also gener...

Oct 06, 2017

C-X-C chemokine receptors (CXCR) is a family of G protein-coupled receptors that comprises of a large subfamily of the rhodopsin superfamily of 7-transmembrane domain receptors. Two types of chemokine receptors have been identified including monogamous chemokine receptors (bind to only one specific chemokine) and pr...

Sep 28, 2017

Another flop for Alzeimer’s as Late Stage drug of AxovantSciences fails in trial Axovant Sciences has reported the failure of their late-stage trial involving the testing of its pill Intepirdinecould not suppress Alzheimer's symptoms in participants of the trail. The news had plunged the Wall Street into another wav...

Sep 22, 2017

The enzyme, isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate and CO2. It is found in the cytosol, mitochondrial matrix, and peroxisomes. IDH is responsible for cellular respiration in the TCA cycle. Isocitrate dehydrogenase exists in three isoforms i...

Sep 20, 2017

Chinese pharma company Shanghai Fosun to acquire 74% stake in Indian company Gland Pharma for $1.09 billion In July last year Chinese company Shanghai Fosun Pharmaceutical announced to acquire 74% per cent stake in Gland Pharma (Hyderabad-based Company) for not more than USD 1.09 billion. Initially the deal was set...

Sep 18, 2017

Oral Mucositis is a commonly occurring, most debilitating complication of cancer chemotherapy and radiotherapy. It can be characterized by inflammation and ulceration in the oral cavity caused by the chemotherapeutic drugs and radiotherapy used in cancer treatment. Potential complications of oral mucositis include p...

Sep 15, 2017

Bayer and Berkeley Lights embark on a project to automate drug discovery Pharmaceutical giant Bayer and Berkeley Lights have announced their collaboration to conduct a strategic project on a discovery platform aimed to automate antibody discovery and development of cell lines. Bayer and Berkeley Lights’ platform- Be...