Dupixent

Dec 20, 2024

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death globally, according to the World Health Organization (WHO). It affects approximately 251 million people worldwide. Smoking is the leading cause of COPD, responsible for around 70-90% of cases. However, exposure to air pollution, occupa...

Oct 07, 2024

After more than ten years without significant therapeutic advancements in chronic obstructive pulmonary disease (COPD), patients with this progressive condition now have two new treatment options, with more likely to follow. Regeneron and Sanofi recently announced that the FDA has broadened the use of the highly...

Feb 27, 2024

Survodutide Phase II trial Shows Groundbreaking Results in Liver Disease due to MASH, with Significant Improvements in Fibrosis Boehringer Ingelheim has reported that in a Phase II trial, a significant proportion of adults treated with survodutide (BI 456906), up to 83.0%, showed a notable enhancement in metabol...

Feb 09, 2024

Sanofi and Regeneron are prioritizing pediatric care, particularly in their recent progress with the potent anti-inflammatory drug, Dupixent. On January 25, 2024, the FDA approved Dupixent, an IL-4 receptor alpha antagonist, for the treatment of eosinophilic esophagitis (EoE) in children aged 1 to 11, weighing at l...

Aug 14, 2023

Chronic urticarial is a common skin condition characterized by itchy, wheal-and-flare skin reactions or hives. As per Delveinsight analysts, in 2022, there were around 776K individuals in the US affected by chronic urticaria. It can be spontaneous or inducible, lasting more than 6 weeks and persisting for over a ye...

May 31, 2023

DUPIXENT has shown positive pivotal results for COPD, confirming the key role of IL-4 and IL-13 in type 2 inflammatory diseases. DUPIXENT has the potential to be the first biologic with unprecedented and paradigm-shifting clinical results to treat COPD, having demonstrated a statistically significant reduc...

Sep 12, 2022

Key Highlights Tezspire (tezepelumab) with no phenotypic (eosinophilic or allergic) or biomarker restriction will be the new game-changer in the severe asthma marketDepemokimab is an excellent market replacement for GSKs’ Nucala as of its improved binding affinity and longer duration of action as a single doseNo...

May 24, 2022

EU Recommends Approval for PTC Therapeutics’ Gene Therapy Upstaza Upstaza, a gene therapy developed by PTC Therapeutics for patients with the genetic condition AADC deficiency, has been recommended for EU approval, putting another test of gene therapy's commercial prospects in the union. Upstaza (eladocagene exu...

Mar 25, 2022

Dupixent (dupilumab) is a non-immunosuppressive fully human monoclonal antibody that inhibits the signalling of the interleukin-4 (IL-4) and interleukin-13 (IL-13) proteins. According to data from Dupixent clinical trials, IL-4 and IL-13 are key drivers of type 2 inflammation, which is a major contributor to Atopic...

Jun 27, 2019

Sanifit raises USD 80.9 M to advance Calciphylaxis Pipeline Sanifit, a clinical-stage biopharmaceutical company, has raised USD 80.9 million ( €72.2 million ) in total private fundraising. The financing mainly consisted led by Spain’s Caixa Capital Risc, along with many new investors, including Columbus Venture ...