actinic keratosis epidemiology forecast insight
DelveInsight’s ‘Actinic Keratosis–Epidemiology Forecast—2034’ report delivers an in-depth understanding of the Actinic Keratosis, historical and forecasted epidemiology in the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.
Geographies Covered
- The United States
- EU5 (Germany, France, Italy, Spain, and the United Kingdom)
- Japan
Study Period: 2021-2034
Actinic Keratosis Disease Understanding
Actinic Keratosis (AK) referred to as solar keratosis is a rough, scaly patch development on skin from years of intense UV rays sun exposure found often on the face, lips, ears, forearms, scalp, neck, and back of the hands.
Actinic Keratosis are dysplastic proliferations of keratinocytes with potential for malignant transformation. Clinically, Actinic Keratosis are warty growths appearing as macules, papules, or hyper-keratotic plaques with an erythematous background where its etiology involves both individual as well as environmental factors.
Actinic Keratosis are diagnosed clinically in majority of the cases. The diagnosis is done by skin examination and confirmed by skin biopsy if needed. Other non-invasive imaging methods, such as confocal microscopy (CM), are useful in specific situations while doubtful cases of Actinic Keratosis require histo-pathological study to confirm the diagnosis.
Actinic Keratosis has a multitude treatment algorithm. Topical treatments include, Imiquimod, Ingenol mebutate, and fluorouracil. Along with the medications prescribed, ablative-surgical treatments such as cryotherapy, scraping (curettage), and laser therapy are included as therapeutic treatment options for treating Actinic Keratosis patients.
Actinic Keratosis represents a cutaneous condition with an impact on quality of life, and they are an important precursor of cutaneous neoplasias. For this reason, the recognition and prompt treatment of Actinic Keratosis lesions are of extreme importance, since progression of the disease can be prevented.
Actinic Keratosis Epidemiology
The Actinic Keratosis epidemiology division provides insights about the historical and current patient pool along with the forecasted trend for every seven major countries. It helps recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the DelveInsight report also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Key Findings
The disease epidemiology covered in the report provides historical as well as forecasted Actinic Keratosis epidemiology segmented as the Total Diagnosed Prevalence of Actinic Keratosis, Gender-based Prevalence of Actinic Keratosis, and Age-based Prevalence of Actinic Keratosis. The report includes the Prevalent scenario of Actinic Keratosis in 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom), and Japan from 2021 to 2034.
Country Wise- Actinic Keratosis Epidemiology
- The epidemiology segment also provides the Actinic Keratosis epidemiology data and findings across the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
- The total prevalent population of Actinic Keratosis associated in 7MM countries was estimated to be 18,524,000 cases in 2020 and expected to increase at a CAGR of 0.54% for the study period, i.e., 2021-2034.
- As per the estimates, United States has the highest prevalent population of Actinic Keratosis in 7MM.
- Among the EU5 countries, Germany had the highest prevalent population of Actinic Keratosis. On the other hand Spain had the lowest prevalent population. In 7MM, Japan had the lowest number of cases, 527,934 cases in 2020.
Scope of the Report
- Actinic Keratosis report covers a detailed overview explaining its causes, symptoms, classification, pathophysiology, diagnosis, and treatment patterns
- Actinic Keratosis Epidemiology Report and Model provide an overview of the risk factors and global trends of Actinic Keratosis in the seven major markets (7MM: US, France, Germany, Italy, Spain, UK, and Japan)
- The report provides insight into the historical and forecasted patient pool of Actinic Keratosis in the seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan
- The report helps recognize the growth opportunities in the 7MM concerning the patient population
- The report assesses the disease risk and burden and highlights the unmet needs of Actinic Keratosis
- The report provides the segmentation of the Actinic Keratosis epidemiology by prevalent Cases of Actinic Keratosis in 7MM
- The report provides the segmentation of the Actinic Keratosis epidemiology by Total diagnosed Prevalence of Actinic Keratosis, Prevalence of Actinic Keratosis based on Gender specific factors, Age-specific cases of Actinic Keratosis in 7MM
Report Highlights
- 10-year Forecast of Actinic Keratosis epidemiology
- 7MM Coverage
- Total Diagnosed Prevalent Cases of Actinic Keratosis
- Prevalent Cases of Actinic Keratosis based on age-specific Factors
- Gender-specific Prevalence of Actinic Keratosis
KOL Views
We interview KOLs, and SME’s opinion through primary research to fill the data gaps and validate our secondary research. The opinion helps understand the total patient population and current treatment pattern. This will support the clients in potential upcoming novel treatment by identifying the overall scenario of the indications.
Key Questions Answered
- What will be the growth opportunities in the 7MM concerning the patient population about Actinic Keratosis?
- What are the Key Findings of Actinic Keratosis epidemiology across 7MM, and which country will have the highest number of patients during the forecast period (2025-2034)?
- What would be the total number of patients with Actinic Keratosis across the 7MM during the forecast period (2025-2034)?
- Among the EU5 countries, which country will have the highest number of patients during the forecast period (2025-2034)?
- At what CAGR the patient population is expected to grow by 7MM during the forecast period (2025-2034)?
- What are the disease risk, burden, and unmet needs of Actinic Keratosis?
- What are the currently available treatments for Actinic Keratosis?
Reasons to buy
The Actinic Keratosis Epidemiology report will allow the user to -
- Develop business strategies by understanding the trends shaping and driving the global Actinic Keratosis market
- Quantify patient populations in the global Actinic Keratosis market to improve product design, pricing, and launch plans
- Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for Actinic Keratosis therapeutics in each of the markets covered
- Understand the magnitude of Actinic Keratosis population by its prevalent cases
- Understand the magnitude of Actinic Keratosis population by its clinical manifestation specific cases
- The Actinic Keratosis epidemiology report and model was written and developed by Masters and PhD level epidemiologists
- The Actinic Keratosis Epidemiology Model developed by DelveInsight is easy to navigate, interactive with dashboards, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over a 10-year forecast period using reputable sources
Key Assessments
- Patient Segmentation
- Disease Risk and Burden
- Risk of disease by the segmentation
- Factors driving growth in a specific patient population
1. Key Insights
2. Report Introduction
3. Actinic Keratosis Market Overview at a Glance
3.1. Market Share (%) Distribution Actinic Keratosis in 2018
3.2. Market Share (%) Distribution of Actinic Keratosis in 2030
4. Executive Summary of Actinic Keratosis
5. Organizations contributing towards Actinic Keratosis
6. Disease Background and Overview
6.1. Introduction
6.2. Signs and Symptoms
6.3. Classification Systems
6.4. Clinical variants of Actinic Keratosis
6.5. Pathogenesis
6.6. Pathophysiology
6.7. Genetic Basis of Actinic Keratosis
6.8. Causes and Risk factors for Actinic Keratosis
6.9. Diagnosis
7. Treatment and Management
7.1. Treatment goals
7.2. Lesion-Directed Therapies: First line treatment
7.3. Field-Directed Therapies: Topical therapies
7.4. Photodynamic therapy
7.5. British Association of Dermatologists Guidelines for the care of patients with Actinic Keratosis 2017
7.6. American Academy of Dermatology
7.6.1. Guideline highlights
7.7. Evidence and consensus based (S3) Guidelines for the Treatment of Actinic Keratosis
7.8. Japanese Dermatological Association
8. Epidemiology and Patient Population
8.1. Key Findings
8.2. Total Prevalent Patient Population of Actinic Keratosis
8.3. Assumption and Rationale
8.4. The United States
8.4.1. Total Diagnosed Prevalent Cases of Actinic Keratosis in the United States
8.4.2. Prevalence of Actinic Keratosis based on Gender in the United States
8.4.3. Prevalence of Actinic Keratosis based on Age in the United States
8.5. EU5
8.5.1. Germany
8.5.1.1. Total Diagnosed Prevalent Cases of Actinic Keratosis in Germany
8.5.1.2. Prevalence of Actinic Keratosis based on Gender in Germany
8.5.1.3. Prevalence of Actinic Keratosis based on Age in Germany
8.5.2. France
8.5.2.1. Total Diagnosed Prevalent Cases of Actinic Keratosis in France
8.5.2.2. Prevalence of Actinic Keratosis based on Gender in France
8.5.2.3. Prevalence of Actinic Keratosis based on Age in France
8.5.3. Italy
8.5.3.1. Total Diagnosed Prevalent Cases of Actinic Keratosis in Italy
8.5.3.2. Prevalence of Actinic Keratosis based on Gender in Italy
8.5.3.3. Prevalence of Actinic Keratosis based on Age in Italy
8.5.4. Spain
8.5.4.1. Total Diagnosed Prevalent Cases of Actinic Keratosis in Spain
8.5.4.2. Prevalence of Actinic Keratosis based on Gender in Spain
8.5.4.3. Prevalence of Actinic Keratosis based on Age in Spain
8.5.5. United Kingdom
8.5.5.1. Total Diagnosed Prevalent Cases of Actinic Keratosis in United Kingdom
8.5.5.2. Prevalence of Actinic Keratosis based on Gender in United Kingdom
8.5.5.3. Prevalence of Actinic Keratosis based on Age in United Kingdom
8.6. Japan
8.6.1. Total Diagnosed Prevalent Cases of Actinic Keratosis in Japan
8.6.2. Prevalence of Actinic Keratosis based on Gender in Japan
8.6.3. Prevalence of Actinic Keratosis based on Age in Japan
9. Patient Journey
10. Case Report
11. KOL Views
12. Unmet Needs
13. Appendix
13.1. Bibliography
13.2. Report Methodology
14. DelveInsight Capabilities
15. Disclaimer
16. About DelveInsight
List of Tables:
List of Table
Table 1: Summary of Actinic Keratosis, Market, Epidemiology, and Key Events (2021-2034)
Table 2: Organizations contributing towards Actinic Keratosis
Table 3: Clinical variants of Actinic Keratosis Criteria for Grading KIN
Table 4: Reclassification of Actinic Keratosis
Table 5: Clinical grading system (according to Olsen 1991)
Table 6: Risk factors for the development of basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs)
Table 7: Diagnostic Criteria for Actinic Keratosis
Table 8: European Medicines Agency Approval Status of Ranked Treatments for Actinic Keratosis
Table 9: Therapies recommended for Actinic Keratosis based on Severity
Table 10: British guidelines for treatment of Actinic Keratosis
Table 11: Key recommendations
Table 12: Overview of the recommendations for the treatment of Actinic Keratosis
Table 13: A practical report and treatment algorithm from Actinic Keratosis Team expert clinicians
Table 14: Japanese guidelines for treatment of Actinic Keratosis
Table 15: Prevalent Patient Population of Actinic Keratosis in 7 MM (2021-2034)
Table 16: Prevalent Cases of Actinic Keratosis in the United States (2021-2034)
Table 17: Prevalence of Actinic Keratosis based on Gender in the United States (2021-2034)
Table 18: Prevalence of Actinic Keratosis based on Age in the United States (2021-2034)
Table 19: Total Diagnosed Prevalent Cases of Actinic Keratosis in Germany (2021-2034)
Table 20: Prevalence of Actinic Keratosis based on Gender in Germany (2021-2034)
Table 21: Prevalence of Actinic Keratosis based on Age in Germany (2021-2034)
Table 22: Total Diagnosed Prevalent Cases of Actinic Keratosis in France (2021-2034)
Table 23: Prevalence of Actinic Keratosis based on Gender in France (2021-2034)
Table 24: Prevalence of Actinic Keratosis based on Age in France (2021-2034)
Table 25: Total Diagnosed Prevalent Cases of Actinic Keratosis in Italy (2021-2034)
Table 26: Gender specific Prevalence of Actinic Keratosis in Italy (2021-2034)
Table 27: Prevalence of Actinic Keratosis based on Age in Italy (2021-2034)
Table 28: Total Diagnosed Prevalent Cases of Actinic Keratosis in Spain (2021-2034)
Table 29: Prevalence of Actinic Keratosis based on Gender in Spain (2021-2034)
Table 30: Age specific Prevalence of Actinic Keratosis in Spain (2021-2034)
Table 31: Total Diagnosed Prevalent Cases of Actinic Keratosis in the UK (2021-2034)
Table 32: Gender specific Prevalence of Actinic Keratosis in the UK (2021-2034)
Table 33: Prevalence of Actinic Keratosis based on Age in the UK (2021-2034)
Table 34: Total Diagnosed Prevalent Cases of Actinic Keratosis in Japan (2021-2034)
Table 35: Prevalence of Actinic Keratosis based on Gender in Japan (2021-2034)
Table 36: Prevalence of Actinic Keratosis based on Age in Japan (2021-2034)
List of Figures:
List of Figures
Figure 1: Signs and Symptoms of Actinic Keratosis
Figure 2: Clinical variants of Actinic Keratosis
Figure 3: Mechanisms involved in actinic Actinic Keratosis pathogenesis.
Figure 4: Causes of Actinic Keratosis
Figure 5: Proposed algorithm for treatment of Actinic Keratosis
Figure 6: Signs and Symptoms of Actinic Keratosis
Figure 7: Treatment Algorithm Based on Expert Consensus
Figure 8: Prevalent Patient Population of Actinic Keratosis in 7MM (2021-2034)
Figure 9: Total Diagnosed Prevalent Cases of Actinic Keratosis in the United States (2021-2034)
Figure 10: Prevalence of Actinic Keratosis based on Gender in the United States (2021-2034)
Figure 11: Prevalence of Actinic Keratosis based on Age in the United States (2021-2034)
Figure 12: Total Diagnosed Prevalent Cases of Actinic Keratosis in Germany (2021-2034)
Figure 13: Prevalence of Actinic Keratosis based on Gender in Germany (2021-2034)
Figure 14: Prevalence of Actinic Keratosis based on Age in Germany (2021-2034)
Figure 15: Total Diagnosed Prevalent Cases of Actinic Keratosis in France (2021-2034)
Figure 16: Prevalence of Actinic Keratosis based on Gender in France (2021-2034)
Figure 17: Prevalence of Actinic Keratosis based on Age in France (2021-2034)
Figure 18: Total Diagnosed Prevalent Cases of Actinic Keratosis in Italy (2021-2034)
Figure 19: Prevalence of Actinic Keratosis based on Gender in Italy (2021-2034)
Figure 20: Prevalence of Actinic Keratosis based on Age in Italy (2021-2034)
Figure 21: Total Diagnosed Prevalent Cases of Actinic Keratosis in Spain (2021-2034)
Figure 22: Prevalence of Actinic Keratosis based on Gender in Spain (2021-2034)
Figure 23: Prevalence of Actinic Keratosis based on Age in Spain (2021-2034)
Figure 24: Total Diagnosed Prevalent Cases of Actinic Keratosis in the UK (2021-2034)
Figure 25: Gender specific Prevalence of Actinic Keratosis in the UK (2021-2034)
Figure 26: Prevalence of Actinic Keratosis based on Age in the UK (2021-2034)
Figure 27: Total Diagnosed Prevalent Cases of Actinic Keratosis in Japan (2021-2034)
Figure 28: Prevalence of Actinic Keratosis based on Gender in Japan (2021-2034)
Figure 29: Prevalence of Actinic Keratosis based on Age in Japan (2021-2034)