congestive heart failure chf epidemiology forecast

Key Highlights

• Chronic heart failure is more prevalent than acute heart failure in the 7MM.
• The largest number of prevalent cases have been observed in the United States. On the other hand, among EU4 and the UK, the largest number of heart failure cases were observed in Germany.
• As per the estimates, the total diagnosed prevalent cases of CHF in the US were approximately 7,550,000 in 2023, and males are more prevalent than females.
• In 2023, NYHA class II specific cases accounted for the highest, that is around 3,200,000 cases in the US.
• The signs and symptoms of CHF are subtle at the initial stage, and these are generally misguided for common signs of aging. The common symptoms of CHF are because of extra fluid or congestion, which leads to vessel blocking. 

DelveInsight’s “Congestive Heart Failure (CHF) – Epidemiology – 2034” report delivers an in-depth understanding of CHF, historical and forecasted epidemiology of CHF in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

Geography Covered

• The United States
• EU4 (Germany, France, Italy, and Spain) and the United Kingdom
• Japan

Study Period: 2021-2034

Congestive Heart Failure (CHF) Disease Understanding 

Congestive Heart Failure Overview

Congestive heart failure commonly referred to as heart failure is a chronic progressive condition in which the heart cannot generate a cardiac output sufficient to meet the body’s demands without increasing diastolic pressure resulting from any cardiac disease compromising ventricular systolic or diastolic function. The common term for describing heart failure is based on left ventricular ejection fraction. Also, heart failure with normal LVEF (≥50%) is known as heart failure with preserved ejection fraction and heart failure with decreased LVEF (<40%) as heart failure with reduced ejection fraction. Heart failure with a 40–49% middle range is known as heart failure with mid-range ejection fraction (HFmrEF).

CHF Diagnosis

The assessment for congestive heart failure is achieved using numerous parameters, like physical testing of the patient to know the occurrence of clinical symptoms of heart failure, various blood tests, urine analysis, fasting glucose, and lipid profile, metabolic profiling for serum electrolytes, and thyroid hormone estimation. Apart from these routine tests, different imaging techniques like chest X-ray, ECG, MRI, and others are used for diagnosing CHF.

Further details related to diagnosis are provided in the report…

Congestive Heart Failure (CHF) Epidemiology 

As the market is derived using the patient-based model, the congestive heart failure epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by total diagnosed prevalent cases of heart failure, gender-specific cases of heart failure, age-specific cases of heart failure, NYHA class-specific cases of heart failure, ejection fraction-specific cases of heart failure, and type-specific cases of heart failure (acute and chronic) in the 7MM covering the United States, EU4 (Germany, France, Italy, Spain) and the United Kingdom, and Japan from 2021 to 2034.

Key findings

• Driven by multiple factors, the number and distribution of reported cases of CHF have increased over time in the 7MM, among which the United States contributed the major patient share.
• As per the estimates, the total diagnosed prevalent cases of congestive heart failure in the 7MM were approximately 21 million in 2023, and males are more prevalent than females.
• The analysis of CHF in the 7MM draws a clear scenario which showed that the patients with HFpEF have a larger proportion (i.e., ~50%) because the heart is not severely affected whereas, in the case of HFrEF, the patient’s heart is majorly affected. W ith growing age, the pumping rate of the heart declines.
• In 2023, among all the four NYHA Classes of heart failure, Class II accounted for around 45% of the total diagnosed heart failure cases in the 7MM.
• Maximum cases of heart failure fall in the age group of ≥ 60 years. In 2023, approximately 6.8 million cases of heart failure in the US belonged to this age group.
• In 2023, among EU4 and the UK, the largest number of heart failure cases were observed in Germany, followed by France and Spain, whereas the United Kingdom accounted for the smallest number of cases in the 7MM

KOL Views

To keep up with current epidemiology trends, we take KOLs and SMEs’ opinions working in the domain through primary research to fill the data gaps and validate our secondary research. Industry experts contacted for insights on the CHF evolving epidemiology landscape, patient reliance on conventional therapies, patient therapy switching acceptability, and drug uptake, along with challenges related to accessibility, including Hematologists, Rheumatologists, Hematology-Oncology specialists, and others.

DelveInsight’s analysts connected with 30+ KOLs to gather insights; however, interviews were conducted with 15+ KOLs in the 7MM. Centers such as Royal Brompton and Harefield NHS Foundation Trust, George Institute for International Health, etc., were contacted. Their opinion helps understand and validate the epidemiology trend in different geographies.